Data for the paper: "Positive interactions of mechanical loading and PTH treatments on spatio-temporal bone remodelling"

Data used in the paper : "Bone remodelling in the mouse tibia is spatio-temporally modulated by oestrogen deficiency and external mechanical loading: a combined in vivo/ in silico study"byVS Cheong, BC Roberts, V Kadirkamanathan, E Dall'Ara (2021)published in Acta BiomaterialiaWe share here an example of in vivo microCT images collected for a mouse that underwent the following interventions:-ovariectomy at week 14 of age - mechanical loading at week 19 and 21 of age.- injections of Parathyroid hormone (PTH; 5 days per week) between weeks 18 and 22 of ageIn vivo 3D microCT images of the mouse tibia have been acquired at week 14, 18, 20, and 22 of age.The registered and cropped images are reported here.In case the reader is interested in the whole database they should contact Dr Enrico Dall'Ara ([e-mail]).

本文所采用的数据集来源于 VS Cheong、BC Roberts、V Kadirkamanathan、E Dall'Ara 等人于 2021 年发表的论文《小鼠胫骨骨重塑受雌激素缺乏及外部机械负荷的时空调节：一项结合体内/体外研究》。本研究中，我们分享了一例针对小鼠进行的干预措施所收集的体内微CT图像示例，包括：于14周龄时进行卵巢切除术；于19周龄和21周龄时施加机械负荷；以及于18周龄至22周龄期间每周注射甲状旁腺激素（PTH）5天。在14周龄、18周龄、20周龄和22周龄时获取了小鼠胫骨的体内3D微CT图像。此处报告了已注册并裁剪的图像。如读者对整个数据库感兴趣，请联系 Enrico Dall'Ara 博士（[e-mail]）。