YY1 Interacts with G quadruplex DNA to Regulate Gene Expression
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https://www.ncbi.nlm.nih.gov/sra/SRP237753
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资源简介：
We systematically analyzed the alterations in mRNA transcriptome evoked by knockdown of YY1 with or without pyridostatin (PDS) treatment. Statistical analysis showed a strong correlation between PDS-regulated and YY1-regulated genes (Pearson r > 0.67), underscoring the role of YY1-G4 structure interaction in YY1-mediated gene regulation. Moreover, the RNA-Seq results revealed that YY1 can positively or negatively regulate the expression of genes through its interaction with G4 structures. Overall design: Examination of gene expression after knockdown of YY1 with or without pyridostatin (PDS) treatment
创建时间：
2020-08-30
