Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p
1(includes reciprocal interactions). Topological parameters for T. pallidum protein datasets and corresponding networks were calculated using the NetAnalyzer plugin for Cytoscape (http://med.bioinf.mp
Among other effects, post-translational modifications (PTMs) have been shown to exert their function via the modulation of protein-protein interactions. For twelve different main PTM-types and associa