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Cell-intrinsic tumorigenic functions of PPARg in bladder urothelial carcinoma [RNA-seq]. Cell-intrinsic tumorigenic functions of PPARg in bladder urothelial carcinoma [RNA-seq]

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NIAID Data Ecosystem2026-03-12 收录
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PPARg promotes UC progression through cell-autonomous mechanisms linked to sonic hedgehog (SHH) signaling. Overall design: Treatment of UC cells with PPARg inverse agonist or PPARG deletion reduces proliferation, migration, and invasion of multiple UC cell lines. Genome-wide approaches define a novel set of PPARg-regulated genes in UC, including SHH.

创建时间:
2021-02-15
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