Pan-chiropteran protein database and pre-computed indices (BLASTP/DIAMOND/MMSeqs2) for homology search

This repository provides a protein database with sequences derived from TOGA2 runs using human, mouse, cow and elephant as references. For each gene, the longest fully intact, intact or partially intact projection was retained. Additionally, pre-computed incdices for immediate use with BLASTP, DIAMOND and MMSeqs2 are provided. Database Version Source Date Pan-chiroptera Release 2026_08 chiroptera.protein.fa.gz 2026-07-16 Included files chiroptera.protein.fa.gz – Original FASTA sequences (68 chiropteran species) blastp_db.tar.gz – BLAST+ database files (.phr, .pin, .psq) diamond_db.tar.gz – DIAMOND database file mmseqs2.tar.gz – MMSeqs2 database + index files Requirements BLAST+ 2.11.0 or higher (for .phr/.pin/.psq files) DIAMOND 2.0.0 or higher (for .dmnd file) MMSeqs2 18.8cc5c or lower (for mmseqs) Usage BLAST+ blastp -db chiroptera_protein -query your_sequences.fasta -out results.txt DIAMOND diamond blastp --db chiroptera_protein -q your_sequences.fasta -o results.txt MMSeqs2 mmseqs easy-search query.fa chiroptera_protein result.m8 tmp Build commands makeblastdb -in chiroptera_protein.fasta -dbtype prot -out chiroptera_protein diamond makedb --in chiroptera_protein.fasta -d chiroptera_proteinmmseqs createindex chiroptera_protein index Species included Species Assembly Carollia perspicillata mCarPer1.2.pri Desmodus rotundus mDesRot1.15.hap1 Diaemus youngii mDiaYou1.3.hap1 Diphylla ecaudata mDipEca1.2.hap1 Brachyphylla cavernarum mBraCav1.1.hap1 Choeroniscus minor mChoMin1.1.hap1 Erophylla bombifrons mEroBom1.1.hap1 Glossophaga mutica mGloMut1.1.hap1 Leptonycteris yerbabuenae mLepYer2.1.hap1 Glyphonycteris daviesi mGlyDav1.1.hap1 Lionycteris spurrelli mLioSpu1.1.hap1 Lonchorhina inusitata mLonInu1.1.hap1 Macrotus waterhousii mMacWat1.1.hap1 Micronycteris megalotis mMicMeg1.1.pri Macrophyllum macrophyllum mMacMac1.1.hap1 Phyllostomus discolor mPhyDis1.3.pri Trachops cirrhosus mTraCir3.1.hap1 Rhinophylla pumilio mRhiPum1.1.hap1 Artibeus intermedius mArtIn1.1.hap1 Centurio senex mCenSen1.1.hap1 Ectophylla alba mEctAlb1.1.hap1 Platyrrhinus guianensis mPlaGui1.1.hap1 Uroderma convexum mUroCon1.1.pri Vampyressa thyone mVamThy1.1.hap1 Cistugo seabrae mCisSea1.1.hap1 Craseonycteris thonglongyai mCraTho2.1.hap1 Rhynchonycteris naso mRhyNas1.2.hap1 Saccopteryx bilineata mSacBil1.1.pri Taphozous melanopogon mTapMel1.1.pri Furipterus horrens mFurHor1.1.pri Aselliscus stoliczkanus mAseSto1.2.pri Doryrhina cyclops mDorCyc1.2.pri Hipposideros abae mHipAba1.1.hap1 Megaderma spasma mMegSpa1.1.pri Miniopterus australis mMinAus1.1.pri Eumops nanus mEumNan1.1.hap1 Molossus alvarezi mMolAlv1.1.hap1 Mops condylurus mMopCon1.1 Tadarida brasiliensis mTadBra1.3.pri Mormoops megalophylla mMorMeg1.1.pri Mystacina tuberculata mMysTub1.2.pri Myzopoda aurita mMyzAur1.1.pri Natalus tumidirostris mNatTum1.1.pri Noctilio leporinus mNocLep2.1.pri Nycteris thebaica mNycThe1.1.hap1 Cynopterus sphinx mCynSph1.1.pri Eonycteris spelaea mEonSpe1.2.hap1 Hypsignathus monstrosus mHypMon1.1.pri Rousettus aegyptiacus mRouAeg1.4.pri Rhinolophus affinis mRhiAff1.2.pri Rhinolophus hipposideros mRhiHip1.1.hap1 Triaenops persicus mTriPer1.1.hap1 Rhinopoma microphyllum mRhiMic1.1.pri Thyroptera tricolor mThyTri1.1.pri Antrozous pallidus mAntPal2.1.pri Cnephaeus nilssonii mEptNil2.1.pri Corynorhinus mexicanus mCorMex1.1.pri Dasypterus ega mLasEga1.1.hap1 Eptesicus fuscus mEptFus1.3.pri Myotis auriculus mMyoAur1.1.pri Myotis daubentonii mMyoDau2.1.pri Myotis lucifugus mMyoLuc2.1.pri Myotis myotis mMyoMyo1.6.pri Myotis vivesi mMyoViv1.2.pri Nyctalus aviator mNycAvi1.1.pri Pipistrellus kuhlii mPipKuh1.2.pri Plecotus auritus mPleAur1.1.pri Vespertilio murinus mVesMur1.1.pri