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Structure of VEGFR2 kinase domain in complex with BIBF1120

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Structure of VEGFR2 kinase domain in complex with BIBF1120 Descriptor: SULFATE ION, Vascular endothelial growth factor receptor 2, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate Authors: Hilberg, F, Roth, G.J, Krssak, M, Kautschitsch, S, Sommergruber, W, Tontsch-Grunt, U, Garin-Chesa, P, Bader, G, Zoephel, A, Quant, J, Heckel, A, Rettig, W.J. Deposit date: 2008-02-08 Release date: 2008-12-23 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res., 68, 2008

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2008-02-08
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