Pharmacoepigenomic impact of Anti-hypertensive drugs on DNA methylation: A genomewide methylation study

Supplementary Materials: The following supporting information can be downloaded at: www.mdpi.com/xxx/s1, Figure S1: Methodology. Figure S2: Up and Down bar plot representing the DMPs that are being discussed in the paper. Table S1: List of primer and the primer sequence of epigenetic genes in the mRNA expression analysis. Table S2: Effect of antihypertensive drugs at varying concentration and duration on the mRNA expression of DNA methyltransferases and DNA demethylases. Table S3: List of common probes and genes that are differentially methylated after AMLO (6-hours and 24-hours) treatment and after ENALA (6-hours and 24-hours) treatment. Table S4: List of probes and genes that were reverted upon duration after treatment. Table S5: List of Gene ontology terms, Fold enrichment, FDR value, Count and Class of each treatment.