MHETase variant Thr159Val, Met192Tyr, Tyr252Phe, Tyr503Trp

NIAID Data Ecosystem2026-05-10 收录

定向进化

PET塑料降解

数据链接：

https://www.rcsb.org/structure/8EKG 数据链接链接失效反馈

官方服务：

资源简介：

MHETase variant Thr159Val, Met192Tyr, Tyr252Phe, Tyr503Trp

创建时间：

2026-03-04

催化元件库的序列数据

定向进化

合成生物学

催化元件库数据集包含了酶催化元件定向挖掘和酶催化元件多目标协同进化数据。通过在土壤中对腈水解酶、腈水合酶等多种酶进行挖掘，将有活性的酶进行基因测序并克隆到表达载体上；通过在数据库对包含腈水解酶、烯烃还原酶、醛酮还原酶、羰基还原酶等在内的多种酶进行筛选，委托生物公司合成酶基因序列，克隆到表达载体上；通过设计的引物对醛酮还原酶、羰基还原酶等在内的多种酶进行定点突变，构建出催化性能增强的酶序列。数据采集

国家基础学科公共科学数据中心130

Replicative RNA enables directed evolution and Darwinian adaptation in mammalian cells

定向进化

哺乳动物细胞

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

Continuous Directed Evolution of a Feedback-Resistant Arabidopsis Arogenate Dehydratase in Plantized Escherichia coli

酶工程

定向进化

Continuous directed evolution (CDE) is a powerful tool for enzyme engineering due to the depth and scale of evolutionary search that it enables. If suitably controlled and calibrated, CDE could be wid

NIAID Data Ecosystem40

RNA sequences PET consortium

PET塑料降解

酶途径转录组分析

RNA was extracted from experimental set of samples with PET plastic and compared to control samples to understand the enzymatic pathways involved in the degradation of PET plastic

NIAID Data Ecosystem90

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 7 Round 5

蛋白质工程

定向进化

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 7 Round 5

NIAID Data Ecosystem50