Transcription profiling of mpuse Dnmt3l-/+ (maternal methylation-deficient) vs normal 8.5dpc embryos

ChEBI2008-06-16 更新2026-07-21 收录

胚胎发育表观遗传

甲基化调控基因

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-8756 数据链接链接失效反馈

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Transcription profiling of mpuse Dnmt3l-/+ (maternal methylation-deficient) vs normal 8.5dpc embryos

创建时间：

2008-06-16

Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization [HiC-seq]

三维基因组学

胚胎发育表观遗传

In mammals, chromosomes are partitioned into megabase-sized topologically associating domains (TADs). TADs can be in either A (active) or B (inactive) subnuclear compartments, which correspond to earl

NIAID Data Ecosystem90

Role of transcription complexes in the formation of the basal methylation pattern in early development

甲基化调控基因

胚胎发育表观遗传

Following erasure in the blastocyst, the entire genome undergoes de novo methylation at the time of implantation, with CpG islands being protected from this process. This bimodal pattern is then pres

NIAID Data Ecosystem40

Characterizing epigenetic effects of HISTONE DEACETYLASE 6 on DNA methylation, siRNA biogenesis and nucleosome positioning using two hda6 alleles in ros1 background. Characterizing epigenetic effects of HISTONE DEACETYLASE 6 on DNA methylation, siRNA biogenesis and nucleosome positioning using two hda6 alleles in ros1 background

甲基化调控基因

siRNA生物合成

DNA cytosine methylation is a hallmark of epigenetic gene silencing. DNA demethylation requires ROS1, a bifunctional DNA glycosylase/lyases and open chromatin status mediated by IDM1. HDA6 is a RDP3-l

NIAID Data Ecosystem20

Principles of nucleation of H3K27 methylation during embryonic development

胚胎发育表观遗传

Polycomb靶点预测

During embryonic development, maintenance of cell identity and lineage commitment requires the Polycomb-group PRC2 complex, which catalyzes histone H3 K27 trimethylation (H3K27me3). However, the devel

NIAID Data Ecosystem60

DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in Neurospora crassa

甲基化调控基因

组蛋白H3K9修饰

DNA methylation is involved in gene silencing and genome stability in organisms from fungi to mammals. Genetic studies in Neurospora crassa previously showed that the CUL4-DDB1 E3 ubiquitin ligase reg

NIAID Data Ecosystem20

Transcription profiling of mpuse Dnmt3l-/+ (maternal methylation-deficient) vs normal 8.5dpc embryos

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