Human PI3K p85alpha/p110alpha
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Human PI3K p85alpha/p110alpha Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Authors: Holliday, M, Tang, Y, Bulku, A, Wilbur, J, Fraser, J. Deposit date: 2023-08-11 Release date: 2023-11-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3K alpha Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia. Cancer Discov, 14, 2024
创建时间：
2023-08-11
