Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence. These chimeric enzymes can be u
aTBMD, total body BMD; FBMD, femur BMD; SBMD, spine BMD.bLocations based on NCBI's Build37 genome assembly.cMAF, minor allele frequency.dNumber of RefSeq genes located in the mouse association CI base