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Senescence rather than apoptosis of alveolar progenitor cells drives pulmonary fibrosis

NIAID Data Ecosystem2026-03-12 收录

肺纤维化机制

细胞衰老研究

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE132915 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2020-10-01

肺纤维化机制

基因表达特征分析

We have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish Mmp19 regulation of fibroblast phenotype changes in mouse lung

NIAID Data Ecosystem80

GATA2 deficiency drives a profibrotic program and metabolic dysfunction in alveolar macrophages

肺纤维化机制

巨噬细胞调控

Alveolar macrophages (AMs) have homeostatic, anti-inflammatory programming to limit tissue damage in response to minor challenge and the distinct, lung-specific function of catabolizing lipid-rich pul

NIAID Data Ecosystem30

Cell competition drives bronchiolization and pulmonary fibrosis. Cell competition drives bronchiolization and pulmonary fibrosis

肺纤维化机制

干细胞竞争

Idiopathic pulmonary fibrosis (IPF) is a progressive respiratory scarring disease arising from the maladaptive differentiation of lung stem cells into bronchial epithelial cells rather than into alveo

NIAID Data Ecosystem20

input_figS1_D_PDI

植物内质网应激机制

细胞衰老研究

This dataset contains data used to generate panel S1D for PDI in a preprint manuscript from the Misteli Lab at the National Cancer Institute/NIH. Title: Activation of endoplasmic reticulum stress in p

Figshare2023-03-10 更新30

Mapping of nucleolus-associated chromosomal domains during replicative senescence.. Homo sapiens

细胞衰老研究

核仁相关结构域

Nucleolus-associated DNA was isolated from cross-linked proliferating and senescent IMR90 human fibroblasts and hybridized against genomic (1) or non-nucleolar (2) DNA to map nucleolus-associated chro

NIAID Data Ecosystem30

Senescence rather than apoptosis of alveolar progenitor cells drives pulmonary fibrosis

资源简介：

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