Effects of CREB5 overexpression on gene expression in Hepatocellular Carcinoma HepG2 cells

In order to investigate the role of CREB5 in HCC cells and find its downstream targets, we overexpressed CREB5 by lentiviral technique and established a stable overexpressed CREB5 hepG2 cell line. Then, two groups of cells (n=3), the control group and the overexpressed group, were used for gene expression profiling. Overall design: Comparative gene expression profiling analysis of RNA-seq data for HepG2 cells (Vecctor, CREB5).