Raw data sets.

Figshare2020-10-26 更新2026-04-28 收录

DNA损伤修复

减数分裂分析

数据链接：

https://figshare.com/articles/dataset/Raw_data_sets_/13145665 数据链接链接失效反馈

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Raw data for plate phenotyping, RAD-51 foci counts in wild-type and rad-54 backgrounds, germ cell apoptosis counts and pHIM-8 foci counts. (XLSX)

创建时间：

2020-10-26

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Approximate LD50 of Aag−/− and Aag transgenic mice to various genotoxic agents.

基因毒性剂测试

DNA损伤修复

MMS, Methyl methanesulfonate; MNU, N-methyl-N-nitrosourea; AOM, Azoxymethane; MMC, Mitomycin C; CAA, Chloroacetaldehyde.*Indicates that the Aag transgene is expressed in an Aag−/− background.

Figshare2015-12-02 更新10

A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination

DNA损伤修复

染色体重组

Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to DNA double-strand breaks (DSBs) that will be preferentially repaired by homologo

Figshare2017-05-19 更新10

Crystal structure of DPO4 with 8-oxoadenine (oxoA) and dTTP*

DNA损伤修复

晶体结构解析

Crystal structure of DPO4 with 8-oxoadenine (oxoA) and dTTP*

NIAID Data Ecosystem20

Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients.

皮肤癌突变谱

DNA损伤修复

The UV component of sunlight is the major carcinogen involved in the etiology of skin cancers. We have studied the rare, hereditary syndrome xeroderma pigmentosum (XP), which is characterized by a ver

PubMed Central1993-11-15 更新10

Raw data sets.

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