Additional file 1 of Comparative analysis of Rosetta stone events in Klebsiella pneumoniae and Streptococcus pneumoniae for drug target identification

Additional file 1: Supplementary table 1. Proteins containing common domains and their domain repertoir. These proteins of SPD39 contain one or more of the common domains between the two microbes. Their tethering patterns with other domains account for the domain versatility, while the number of occurence accounts for abundance. Supplementary table 2. Proteins containing common domains and their domain repertoir. These proteins of KPNIH11 contain one or more of the common domains between the two microbes. Their tethering patterns with other domains account for the domain versatility, while the number of occurence accounts for abundance. Supplementary table 3. Protein annotation using PSI-BAST. These proteins of SPD39 have been annotated using PSI-BLAST and checked for homology with human proteome using DELTA-BLAST. All the proteins except ABJ54307 and ABJ55037 were found non-homologous to human proteomemaking them ideal drug targets. Supplementary table 4. Protein annotation using PSI-BLAST. These proteins of KPNIH11 have been anntated using PSI-BLAST and checked for homology with human proteome using DELTA-BLAST. All the proteins were found non-homologous to human proteomemaking them ideal drug targets. Supplementary table 5. Virtual screening results of TCM databse ligands. This list of ligands showed affinity towars EJJ83173 protein during docking. These are Traditional Chineses Medicine that can be targeted to interfere protein function of EJJ83173. Supplementary table 6. Virtual screening results of ZINC databse ligands. This list of ligands showed affinity towars EJJ83173 protein during docking. These are commercially available drugs that can be targeted to interfere protein function of EJJ83173.