Sequence alignment of RNA-seq identified SNPs. The alignment for each locus included sequences from the following three sources: reference sequence (with RefSeq in the label), sequence generated using
We recently developed the rG4-seq method to detect and map in vitro RNA G-quadruplex (rG4s) structures on a transcriptome-wide scale. rG4-seq of purified human HeLa RNA has revealed many non-canonical
Table provides a summary of computational resources used for each step in our assembly pipeline (Fig 1A). Columns reflect an identifier for the pipeline step, bioinformatics tool used, the total numbe