Crystal structure of FGFR4(V550M) kinase domain with 10z
收藏Protein Data Bank Japan2024-11-13 更新2026-04-25 收录
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Crystal structure of FGFR4(V550M) kinase domain with 10z Descriptor: Fibroblast growth factor receptor 4, SULFATE ION, ~{N}-[4-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-5-cyano-pyridin-2-yl]-6-bromanyl-5-(hydroxymethyl)-1-(2-morpholin-4-ylethyl)pyrrolo[3,2-b]pyridine-3-carboxamide Authors: Chen, X.J, Lin, Q.M, Chen, Y.H. Deposit date: 2022-06-30 Release date: 2022-11-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.233 Å) Cite: Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2- b ]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors. J.Med.Chem., 65, 2022
创建时间：
2022-06-30
