Selection of target proteins.

A. The selection pipeline used for investigating computationally predicted adhesins. B. Logic table for combining the results from predictions using multiple algorithms. Predictions from various algorithms were considered for the hypothesis of “adhesin and surface localized” in the forms of Claims (supporting) and Attacks (not-supporting) associated with their confidence of predictions in three categories, High, Medium and Low. Several cases could not be resolved and they remained “undecided” in our protocol.