Baseline subject and disease characteristics.

Data is presented as mean ± SE. Differences between groups (SED, HCTR and HITR) were analysed by a one-way ANOVA. Abbreviations used: MS, multiple sclerosis; SED, sedentary group; HCTR, intense continuous endurance + resistance training; HITR, high intensity interval training + resistance training, BMI, body mass index; RR, relapsing remitting; CP, chronic progressive; EDSS, expanded disability status scale; immunomodulatory: interferon β, glatiramer acetate, fingolimod, natalizumab.