KRasG12C ligand complex
收藏Protein Data Bank Japan2025-10-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6t5u
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KRasG12C ligand complex Descriptor: 1-[(7R)-16-chloro-15-(5-methyl-1H-indazol-4-yl)-9-oxa-2,5,12-triazatetracyclo[8.8.0.02,7.013,18]octadeca-1(10),11,13,15,17-pentaen-5-yl]prop-2-en-1-one, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Phillips, C. Deposit date: 2019-10-17 Release date: 2020-02-19 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. J.Med.Chem., 63, 2020
创建时间：
2019-10-17
