Hypoxia and dimethyloxalylglycine (DMOG) downregulates tryptophan-2,3-dioxygenase (TDO2) expression in GBM cells. Hypoxia and dimethyloxalylglycine (DMOG) downregulates tryptophan-2,3-dioxygenase (TDO2) expression in GBM cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA576263
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资源简介:
The tryptophan degrading enzyme TDO2 is downregulated upon HIF1alpha stabilization by exposure to both hypoxia as well as chemical hypoxia mimetics such as DMOG in glioblastoma cell line A172. Overall design: Hypoxia: expression profile of A172 cells under hypoxic (1% oxygen) and normoxic (18.6% oxygen) conditions after 5 days (n = 5). DMOG: expression profile of A172 cells treated with 3mM dimethyloxalylglycine (DMOG) for 24 hours compared to EtOH control (n=3).
创建时间:
2019-10-07



