Structure of Focal Adhesion Kinase catalytic domain in complex with hinge binding pyrazolobenzothiazine compound.
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Structure of Focal Adhesion Kinase catalytic domain in complex with hinge binding pyrazolobenzothiazine compound. Descriptor: Focal adhesion kinase 1, [4-(2-hydroxyethyl)piperidin-1-yl][4-(5-methyl-4,4-dioxido-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-yl)phenyl]methanone Authors: Skene, R.J, Hosfield, D.J. Deposit date: 2012-11-27 Release date: 2013-03-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure-based discovery of cellular-active allosteric inhibitors of FAK. Bioorg.Med.Chem.Lett., 23, 2013
创建时间：
2012-11-27
