Human proteins released into the medium in top of the 3D-liver model.

Proteome data after BLAST search with the H. sapiens UniProt database (samples from 4 biological replicates) were cleaned from possible bovine serum contaminants by eliminating any peptides or proteins shared with bovine species. A total of 64 proteins having at least one human-specific peptide was identified (see Table S1 and S2). A literature search and the information contained in the UniProtKB/Swiss-Prot database identified 45 proteins known for being released or secreted. Proteins were grouped according to their main function given in the UniProtKB/Swiss-Prot database and organized by the alphabetical order of the database accession numbers. Bold-labelled entries correspond to those proteins for which hepatic cells are known to be the exclusive or a main site of synthesis. The numbers given are average from all samples. PSMS is peptide spectrum matches, MW molecular weight.Human proteins released into the medium in top of the 3D-liver model.