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CTCF binding strength defines regions of genome fragility facilitated by TOP2 and alternative DNA secondary structure

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NIAID Data Ecosystem2026-03-13 收录
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This study set out to map DNA double-stranded breaks (DSBs) in breast cells to better understand fragility associated with CTCF overall, and how changes in CTCF expression or binding relates to genome instability and cancer development.

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2022-01-07
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