Positional enrichment analysis identified age-related genes that were over-represented on 4 chromosomes including Chromosome 1 and 13.

A plot of selected genes found to be over-represented at 1q12 and 13q21. A) Positional enrichment analysis identified 3 genes at each loci and B) the relationship with age of each gene was plotted with the linear correlation coefficient provided and the FDR derived from the qSAM analysis (FDR<5%). Genes at these loci included proteins that are known to influence mTOR related signalling.