首页/数据集/Sustained NF-kB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation

Sustained NF-kB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation

NIAID Data Ecosystem2026-05-02 收录

肿瘤起始机制

肺泡干细胞生物学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE247505 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-07-28

肿瘤起始机制

干细胞重编程

We address the molecular mechanisms through which MYC promotes loss of cell identity and acquisition of stem cell-like traits, favouring the onset of tumorigenesis, by performing gene expression profi

NIAID Data Ecosystem70

Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3

乳腺癌干细胞调控

肿瘤起始机制

Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive cancers and are thought to promote their growth and progression. TCF3 (also known as TCF7L1) is a memb

NIAID Data Ecosystem50

Cell state transitions regulated by Slug are critical for tissue regeneration and tumor initiation

细胞可塑性调控

肿瘤起始机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem10

Pancreatic cancer cell upregulates LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumor initiation

胰腺癌微环境

肿瘤起始机制

Patient-derived pancreatic cancer cells 79E cells stably transfected with empty vector or LPAR4 gene were treated with or without LPA for 2 hours, and then RNA was extracted from these cells for RNA-s

Figshare2023-01-17 更新60

Cell state transitions regulated by Slug are critical for tissue regeneration and tumor initiation

细胞可塑性调控

肿瘤起始机制

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem20