Neurodevelopmental outcome of preterm very low birth weight infants admitted to an Italian tertiary center over an 11-year period

This database includes the raw data linked with the paper “Neurodevelopmental outcome of preterm very low birth weight infants admitted to an Italian tertiary center over an 11-year period”.

In this paper, we reported the data of perinatal history and neurodevelopmental outcome of a single center cohort of Italian preterm VLBWi born between 2005 and 2015.

The aim of the study is to describe neurodevelopmental outcome at 24 months of corrected age and to identify associations between perinatal risk factors and neurodevelopmental outcome.

502 VLBWi completed the follow up. 75.3% showed a normal outcome, 13.9% minor sequelae and 10.8% major sequelae (3.8% cerebral palsy). Male gender (OR 1.59 CI 95% 1.0-2.5 p value 0.043), bronchopulmonary dysplasia (OR 1.7 CI 95% 1.1-2.9 p value 0.026), abnormal neonatal neurological assessment (OR 2.1 CI 95% 1.3-3.4 p value 0.002) and severe brain ultrasound abnormalities (OR 6.1 IC 95% 2.4-15.1 p value <0.001) were independently associated with poor outcome on multivariate ordered logistic regression.