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Structure of 5 in complex with GDP-KRAS

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Protein Data Bank Japan2025-08-27 更新2026-05-23 收录
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Structure of 5 in complex with GDP-KRAS Descriptor: (4~{S})-2-azanyl-4-methyl-4-[3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]-1,2,4-oxadiazol-5-yl]-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, 1,2-ETHANEDIOL, GTPase KRas, ... Authors: Boettcher, J. Deposit date: 2025-02-11 Release date: 2025-08-06 Last modified: 2025-08-27 Method: X-RAY DIFFRACTION (0.997 Å) Cite: Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy. J.Med.Chem., 68, 2025

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2025-02-11
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