Shah2020 - Predicting Human Liver Microsomal Stability of small molecules
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下载链接：
https://www.omicsdi.org/dataset/biomodels/MODEL2405130005
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资源简介：
The Human Liver Microsomal assay takes into account the liver-mediated drug metabolism to assess the stability of a compound in the human body. The NIH-NCATS group took a proprietary dataset of 4300 compounds with its associated HLM (in vitro half-life; unstable ≤ 30 min, stable >30 min) and used it to train a classifier.
Model Type: Machine learning model.
Model Relevance: Probability of a compound being unstable in a HLM assay.
Model Encoded by: Pauline Banye (Ersilia)
Metadata Submitted in BioModels by: Zainab Ashimiyu-Abdusalam
Implementation of this model code by Ersilia is available here:
https://github.com/ersilia-os/eos31ve
创建时间：
2024-05-13
