Interplay between nutrient stress and lysosomal signaling imprints immune memory in tissues [microarray3]. Interplay between nutrient stress and lysosomal signaling imprints immune memory in tissues [microarray3]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA966164
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Uncovered organelle signaling and metabolic processes shaping CD8+ tissue-resident memory (TRM) development Overall design: OT-1 cells from WT-Cas9-KI-Flcnfl/fl or Cd4Cre-Cas9-KI-Flcnfl/fl mice were transduced with sgNTC, sgTfeb, or sgTfe3 in various combinations as indicated and transferred into WT mice, followed by LM-OVA infection. At day 7.5 p.i., siIEL OT-1 cells were sort purified for microarray analysis
创建时间:
2023-05-02



