B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203
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https://pdbj.org/mine/summary/4fk3
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B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203 Descriptor: N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide, Serine/threonine-protein kinase B-raf Authors: Zhang, Y, Wang, W, Zhang, K.Y.J. Deposit date: 2012-06-12 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc.Natl.Acad.Sci.USA, 105, 2008
创建时间：
2012-06-12
