MIXPRS+ polygenic score files for BMI and CAD
收藏资源简介:
This dataset contains polygenic score (PGS) scoring files generated using the MIXPRS+ framework. Files included:- BMI_EAS_MIXPRSplus- BMI_AFR_MIXPRSplus- CAD_EAS_MIXPRSplus Each file is provided in gzipped tab-delimited text format (.txt.gz) and contains rsID, chromosome, base-pair position, effect allele, other allele, and effect weight (beta). All scores are based on genome build GRCh37. Related manuscript:Xu L, Dong Y, Zeng X, Bian Z, Zhou G, Guan L, Zhao H.Almost Free Enhancement of Multi-Population PRS: From Data-Fission to Pseudo-GWAS Subsampling.bioRxiv 2025.06.16.659952.https://doi.org/10.1101/2025.06.16.659952 This work has been accepted in principle at Nature Genetics with the updated title:MIXPRS enables multi-population and multi-method polygenic risk scores using summary statistics.



