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Transcription profiling of human BCR-ABL1-transformed acute lymphoblastic leukemia cells reveals Activation-induced cytidine deaminase acts as a mutator

ChEBI2008-06-15 更新2026-07-21 收录

淋巴细胞白血病分子机制

转录组学与突变分析

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Transcription profiling of human BCR-ABL1-transformed acute lymphoblastic leukemia cells reveals Activation-induced cytidine deaminase acts as a mutator

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创建时间：

2008-06-15

淋巴细胞白血病分子机制

受体信号通路

This dataset supports the Southampton Doctoral thesis entitled: B-Cell receptor induced autophagy and phagocytosis in chronic lymphocytic leukaemia DESCRIPTION OF THE DATA The following dataset includ

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Effects of Blnk reconstitution in BCR-ABL1 driven pre-B cells. Mus musculus

淋巴细胞白血病分子机制

B细胞受体

In order to investigate the function of the adapterprotein Blnk in ALL, we isolated bone marrow cells from Blnk KO mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven

NIAID Data Ecosystem40

RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]. RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]

淋巴细胞白血病分子机制

Notch信号通路

NOTCH1 gain-of-function mutations are recurrent in B cell chronic lymphocytic leukemia (B-CLL), where they are associated with accelerated disease progression and refractoriness to chemotherapy. The s

NIAID Data Ecosystem30

Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia. Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia

淋巴细胞白血病分子机制

儿童恶性肿瘤转录组学

ETV6/RUNX1 E/R -positive acute lymphoblastic leukemia (ALL), as one of the most common childhood malignancies, its pathogenesis and mechanism remain to be elucidated comprehensively. Global gene expre

NIAID Data Ecosystem60

PI3K/AKT pathway is activated by miRNA-22 in the proliferative CLL subset (miRNA). Homo sapiens

淋巴细胞白血病分子机制

PI3K/AKT信号通路

Understanding the crosstalk between malignant B-cells and their milieu could provide clues on the molecular and clinical biology of Chronic Lymphocytic Leukemia (CLL). Aiming to generate novel therape

NIAID Data Ecosystem30

Transcription profiling of human BCR-ABL1-transformed acute lymphoblastic leukemia cells reveals Activation-induced cytidine deaminase acts as a mutator

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