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Biochemical properties of chromatin domains define their compartmentalization [I]. Biochemical properties of chromatin domains define their compartmentalization [I]
Chromatin three-dimensional (3D) organization inside the cell nucleus determines the separation of euchromatin and heterochromatin domains. Their segregation results in the definition of active and in
NIAID Data Ecosystem60
Aegilops speltoides var. speltoides accession Tivon Hi-C. Aegilops_speltoide_Tivon_Hi-C
Chromosome conformation capture sequencing (Hi-C) data of Aegilops speltoides var. speltoides accession Tivon.
NIAID Data Ecosystem40
The molecular basis of lamin- chromatin interactions [SAMMY-Seq]
Lamins are the main constituents of the nuclear lamina, a fibrillar layer underlying the inner nuclear membrane. The nuclear lamina governs chromatinorganization through lamina-associated domainswithi
NIAID Data Ecosystem30
Additional file 2 of SpectralTAD: an R package for defining a hierarchy of topologically associated domains using spectral clustering
Additional file 2: Table S1. Summary of gaps. The percentage of gaps is summarized for all chromosomes at 10 kb, 25 kb, and 50 kb resolution using raw GM12878 data [3]. Gaps are separated based on whe
Figshare2020-07-20 更新40
SMARCB1 loss creates patient-specific MYC topologies that drive malignant rhabdoid tumor growth [Hi-C]. SMARCB1 loss creates patient-specific MYC topologies that drive malignant rhabdoid tumor growth [Hi-C]
Malignant rhabdoid tumor (MRT) is a highly malignant and often lethal childhood cancer. MRTs are genetically defined by bi-allelic inactivating mutations in SMARCB1, a member of the BRG1/BRM-associate
NIAID Data Ecosystem30
