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Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP288850
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资源简介:
We report results of transcriptional profiling of ex vivo MC38 murine organotypic tumor spheroids following programmed death-1 (PD-1) blockade compared to isotype control IgG treatment by bulk and single-cell RNA-sequencing after 6 days of treatment. Additionally, we report results from single-cell RNA-sequencing of MC38 tumors treated in vivo with PD-1 blockade versus isotype control IgG to validate ex vivo workflow. Overall design: Transcriptional profiling of residual MC38 tumor cells after PD-1 blockade
创建时间:
2021-09-16
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