Synergistic antifungal activity between posaconazole and caspofungin or FK506 against C. albicans drug susceptible or resistant strains.

#Orange highlighting color indicates wild-type and its derived mutants, while yellow and green highlighting colors represent echinocandin resistant and 3 (#1, #9, #17) out of 17 azole resistant isolates from the strain series, respectively.*Formula of FIC index:[(MIC100 of drug A in combination)/(MIC100 of drug A alone)]+[(MIC100 of drug B in combination)/(MIC100 of drug B alone)].FIC≤0.5 (Synergy); FIC >4 (Antagonism); FIC >0.5 but ≤4 (no interaction).