The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroi
Presentation of tissue-restricted antigens (TRA) in the thymus is essentialfor establishing self-tolerancethrough elimination of autoreactive Tcells.It remains unclear why certain self T cell
Systemic Lupus Erythematosus is a chronic autoimmune condition in which the body mistakenly attacks itself. It’s aetiopathogenesis is highly complex. Increasing evidence suggests that the innate immun