Pathways associated with ATP production in lymphoblasts from ALS patients with mutant SOD1 (mutSOD1) or unknown mutation (undSOD1) and respective controls.
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Cells were plated at density 160,000 cells/well, as described in Materials and Methods. Oxygen consumption rate (OCR) and Extracellular Acidification Rate were monitored over time using the Seahorse XFe96 Extracellular Flux Analyzer and the ATP Real-Time rate assay. Data were plotted for all cohorts (pool), C1-Female 46 years old, C2- Male 46 years old and C3-Male 26/27 years old. Several bioenergetic parameters were evaluated.
创建时间:
2022-03-10



