Crystal Structure of Human Beta Secretase Complexed with inhibitor
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Crystal Structure of Human Beta Secretase Complexed with inhibitor Descriptor: Beta-secretase 1, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE, SULFATE ION Authors: Munshi, S. Deposit date: 2007-04-10 Release date: 2008-04-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2007-04-10
