Crystal Structure of BACE with Compound 5
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Crystal Structure of BACE with Compound 5 Descriptor: 1,2-ETHANEDIOL, Beta-secretase 1, DI(HYDROXYETHYL)ETHER, ... Authors: Efremov, I.V, Vajdos, F.F, Borzilleri, K, Capetta, S, Dorff, P, Dutra, J, Mansour, M, Oborski, C, O'Connell, T, O'Sullivan, T.J, Pandit, J, Wang, H, Withka, J. Deposit date: 2011-10-28 Release date: 2012-04-18 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery and optimization of a novel spiropyrrolidine inhibitor of {beta}-secretase (BACE1) through fragment-based drug design. J.Med.Chem., 55, 2012
创建时间：
2011-10-28
