A new subgroup of hepatocellular adenomas with sonic hedgehog pathway activation
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
Hepatocellular adenomas (HCA) are benign liver tumors divided in molecular subtypes characterized by mutations inactivating HNF1A, activating β-catenin or the IL-6/JAK/STAT inflammatory pathway. Molecular analyses of 533 HCA developed in 411 patients identified a new tumor subgroup with Sonic Hedgehog pathway activation due to focal deletions creating INHBE promoter/GLI1 fusions.EGA study EGAS00001002091
创建时间：
2023-09-26
