BIOGRID CURATED DATA FOR HOS3 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for HOS3 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Trichostatin A-insensitive homodimeric histone deacetylase (HDAC); specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats

HOS3（酿酒酵母S288c）的蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）整理；定义：对曲古霉素A不敏感的同源二聚体组蛋白脱乙酰化酶（HDAC）；在体外对组蛋白H3、H4、H2A和H2B具有特异性；与Hda1p、Rpd3p、Hos1p和Hos2p相似；基因缺失导致rDNA重复序列中组蛋白乙酰化水平升高。