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The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma

NIAID Data Ecosystem2026-03-11 收录

滑膜肉瘤

癌蛋白表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108929 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-03-27

滑膜肉瘤

肿瘤分子病理学

The human SYT-SSX fusion protein was expressed in a developmentally dependent fashion in murine myoblasts. Tumors harvested from mice in adolescence were compared to normal mouse skeletal muscle sampl

NIAID Data Ecosystem110

Synovial sarcoma: case report

滑膜肉瘤

头颈部肿瘤病例

ABSTRACT Introduction: Synovial sarcomas are rare and aggressive neoplasms located in the head and neck region and usually occurs in young adults. Presentation of case: This report presents a case o

NIAID Data Ecosystem70

Global Identification of SYT-SSX2 Downstream Genes using Human Pluripotent Stem Cells

基因表达

滑膜肉瘤

We established human pluripotent stem cell (PSC) lines expressing Synovial Sarcoma-specific oncogene, SYT-SSX2, under the control of doxycycline with dose- and time-dependent manner. Gene expression p

NIAID Data Ecosystem60

Supplementary Material for: Poor Treatment Outcomes with Second-Line Chemotherapy in Advanced Synovial Sarcoma

滑膜肉瘤

化疗疗效

Introduction: Synovial sarcoma predominantly affects adolescents and young adults. Doxorubicin with or without ifosfamide therapy is the standard first-line treatment for unresectable or metastatic sy

DataCite Commons2025-05-01 更新90

A novel mouse model for human synovial sarcoma expressing SS18-SSX1

滑膜肉瘤

肿瘤分子机制

SS18-SSX fusion proteins play a central role in synovial sarcoma development, however, genetic network and mechanisms of synovial sarcomagenesis remain largely unknown. To clarify such unknown mechani

NIAID Data Ecosystem60

The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma

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