Additional file 2 of orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control

Additional file 2 It includes all datasets and statistical analysis on which the conclusions are based. Figure 1. P[UAS] insertional mutant exhibits abnormal food-seeking behavior. Figure 2. P[UAS]100B is inserted in CG6115 and encodes a Complex I LYR domain containing protein. Figure 3. A reduction in osi levels affects viability. Figure 4. osi downregulation is associated with a smaller cell size. Figure 5. ETFRF1/LYRm5 rescues cellular and viability defects associated with osi knockdown. Figure 6. Expression of human ETFRF1/LYRm5 rescues lethality associated with osi downregulation in the fat body. Figure S7. A key role for osi in the fat body. Figure 8. osi loss of function produces a metabolic defect not rescued by antioxidants. Figure 9. Preventing excessive fat body lipid catabolism rescues the behavioral effect triggered by osi downregulation. Figure 10. osi mutants have a progressive shift in LD size. Figure 11. Reduced osi levels alters the storage lipid content and composition. Figure 12. A model for Osi function.