Mitochondrial regulation of bone homeostasis via mitochondria transfer [II]
收藏Alliance of Genome Resources2026-08-01 收录
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To reveal an unappreciated mechanism of mitochondrial regulation of skeletal metabolic homeostasis via mitochondria transfer and provide new insights of the mechanism of glucocorticoid-induced osteoporosis progression. MtD2pos and mtD2neg CD11b+ myeloid cells were separated from Prx1creMitodendra+/+ mouse bone marrow and performed unbiased RNA-sequencing to test whether mitochondria transfer from osteolineage to osteoclastic lineage cells is associated with alterations in activities of osteoclastic lineage cells.
