Functional domain analysis.

The proportions of segregating sites in regions of known function versus regions where functions have not been assigned were compared by Fisher's Exact Test (FET) and the resulting probability is listed. Average values of pi(average number of nucleotide differences per site between sequence pairs) were compared between regions of known versus unassigned function using a student's t-test and a significant difference was only seen for R3D1, in which pi was greater in regions of known function.