Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21
收藏Protein Data Bank Japan2024-10-30 更新2026-03-28 收录
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Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21 Descriptor: 2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-(propan-2-yl)-1H-indole, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... Authors: Critton, D.A. Deposit date: 2021-07-07 Release date: 2022-05-04 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8). Acs Med.Chem.Lett., 13, 2022
创建时间:
2021-07-07



