Isolated from the middle-ear of a child with chronic otitis media. Haemophilus influenzae PittHH

Haemophilus influenzae PittHH. Strain PittHH is a non-typeable Haemophilus influenzae (NTHi) isolate recovered by Dr. Robert Wadowsky from the middle-ear effusion of a child in Pittsburgh who was undergoing tympanostomy and ventilation tube placement for the treatment of chronic otitis media with effusion (COME). In the chinchilla model, PittHH infection induces COME and may cause modest systemic disease (which is typically responsive to antibiotics). Sequenced and assembled using technology developed by 454 Life Sciences, Inc. (www.454.com), supplemented with double-barreled Sanger dideoxy sequencing read data from traditional clone libraries. The genome sequence is currently comprised of 73 contigs, and has been sequenced to a depth of 35X.