Caspase-8 expression and its Src dependent phosphorylation on Tyr380 triggers NRF2 signaling activation in glioblastoma

Here we have employed quantitative mass spectrometry based phosphoproteomics and proteomics to characterise the impact of knocking-down the caspase 8 gene in glioblastoma cells. This strategy enabled the identification of the pathways and processes modulated by caspase 8.