REST and Stress Resistance in Aging and AlzheimerM-bM-^@M-^Ys Disease
收藏官方服务：
资源简介：
REST and Stress Resistance in Aging and AlzheimerM-bM-^@M-^Ys Disease
应用场景：
创建时间：
2014-03-16
相关数据集
Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-
Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw
NIAID Data Ecosystem100
AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
NIAID Data Ecosystem40
Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]
GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp
NIAID Data Ecosystem30
Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders
Introduction: Mitochondria (mt) are protein-protein interaction (PPI) hubs in the cell where mt-localized and associated proteins interact in a fashion critical for cell fitness. Altered mtPPIs are li
NIAID Data Ecosystem70
Bassoon proteinopathy drives neurodegeneration in multiple sclerosis
During the course of multiple sclerosis (MS), inflammatory insults drive neuro-axonal loss and disability progression. However, pathways that guide neurons toward survival or death during central nerv
NIAID Data Ecosystem30
